Spectrum of Gastroduodenal Lesions in Endoscopic Biopsies: A Histopathological Study with Endoscopic Correlation

Endoscopy of the gastro intestinal tract is a simple safe and well tolerated procedure, the endoscopic visualisation of the suspected site with biopsy leads to the early detection of the pathologic process and institution of appropriate therapy to the patient. This is a prospective study to find out the spectrum of gastro duodenal lesions diagnosed by histopathology in relation to age & sex distribution, and correlating them with endoscopic findings. Biopsy of 220 gastroduodenal endoscopies during November 2014 – May 2016 was examined. Serial sections, 3 – 5 μ were stained with Haematoxylin & Eosin (H&E) stain. Analysis of 220 cases of Gastroduodenal biopsies was done. Male to female ratio of 1.36: 1 and age range 16 – 85 yrs with commonest age group 41-50 years was observed. 204(92.73%) cases were from stomach and 16(7.27%) from duodenum. Chronic superficial gastritis 175 cases (79.54%) was observed to be most common inflammatory lesion followed by erosive gastritis 16 cases (7.27%), chronic duodenitis 12 cases(5.45%) and gastric carcinoma 8 cases(3.63%). In stomach, chronic superficial gastritis, chronic active gastritis, gastric carcinoma was well correlated with endoscopy findings. No significant correlation of duodenal lesions and endoscopy findings was seen. Chronic superficial gastritis was the most common gastro duodenal lesion followed by erosive gastritis, chronic duodenitis and gastric carcinoma. Significant correlation with endoscopic findings was seen in gastric lesions but not in duodenal lesions.